Week 13 in college football every year is rivalry week, the game between arch-rivals for bragging rights and some playoff hopefuls. In the 2022 season, 9 ranked teams would lose in their rivalry game. It would represent even more as four teams inside of the top 10 would go down and ultimately end their hopes at the College Football Playoff.

#2 Ohio State (11-1) would be upset by #3 Michigan (12-0) by a score of 45-23 at home in Columbus. The Buckeyes came into the game as 9 point favorites and the Wolverines came on the road without star running back Blake Corum, who injured his knee in the week prior against Illinois. Michigan would go into the half down 20-17, but outscore the Buckeyes 28-3 in the second half en route to back to back wins over Ohio State.

#5 LSU (9-3) gets upset on the road by unranked Texas A&M (5-7) by a score of 38-23. The Tigers would come into College Station as massive 10 point favorites, but would fall behind early and go into halftime only down 17-10. The Aggies would break away in the fourth quarter, scoring two touchdowns to set the tone in an upset win that would end all chances for LSU to sneak into the CFP.

#8 Clemson (10-2) falls to a scorching hot, unranked South Carolina (8-4) by a score of 31-30. The Tigers would take a commanding 14-0 lead to start the game, but only lead by 9 going into halftime. The Gamecocks would use a huge third quarter to outscore Clemson by 10 in the second half to upset the Tigers, one week after coming off a dominant, surprise win over a then-ranked, dominant #5 Tennessee team that looked as if they were headed to the CFP.

#9 Oregon (9-3) blows a 28 point lead on the road to #21 Oregon State (9-3) and lose by a score of 38-34. The Beavers would use a three touchdown fourth quarter performance to overcome a 34-10 deficit en route to an upset win over the Ducks, although they came into the game as 1 point favorites.

#15 Notre Dame (8-4) fails its upset bid on the road against #6 USC (11-1) by a score of 38-27. The Trojans proved to be every bit of its 4.5 point favorite, controlling the game and being up as much as 17 points. USC would outscore the Fighting Irish in every quarter and make their case for the College Football Playoff.

#17 North Carolina (9-3) loses 2OT thriller to unranked NC State (8-4) in Chapel Hill by a score of 30-27. The Wolfpack would lead the entire game, coming on the road as 5 point underdogs. On the last play of regulation, North Carolina would score a touchdown from 4 yards out to tie the game. Both teams traded field goals and the Tar Heels would miss a field goal and fail to send the game to triple overtime.

#20 Ole Miss (8-4) fails to convert a two-point conversion in the final minute to get upset by unranked Mississippi State (8-4) in Oxford by a score of 24-22 in the Egg Bowl. The Rebels would be favored by 2.5 points and lead 16-14 at halftime. They did not score again until the last possession of the game, which didn’t prove to be enough and the Bulldogs would win their first Egg Bowl in three years.

#24 Cincinnati (9-3) loses at home for the first time in 32 games to #19 Tulane (10-2) by a score of 27-24. The Green Wave came into the game favored by 1 point and ultimately led the entire game. A touchdown with 5 minutes left in regulation would be the knockout punch as both teams traded scores in each quarter throughout the game.

#25 Louisville (7-5) loses the Governor’s Cup to unranked Kentucky (7-5) in Lexington by a score of 26-13. The Cardinals would fall behind 13-7 at halftime and would also be outscored 13-6 in the second half. The Wildcats would manage and control the game to hold on to win and finish their disappointing season.